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Subproject 1:

Opto-Electronic and Sensing Devices

Subproject 2

Integrated Platform for Intelligent Sensing Chips

Subproject 3

Millimeter-wave and System-in-Package Technologies

Subproject 4

Seamless Connectivity

Subproject 5

Media and Social Cloud Computing with Chinese Flavor

Subproject 6

Intelligent Diagnostic and Therapeutic Care System

 

Subproject 1 : Opto-Electronic and Sensing Devices

    The goal of the proposed efforts in Sub-project 1 is to pursue academic excellence in the areas of opto-electronic and sensing device technologies through working on new device fabrication techniques and novel devices as well as state-of-the-art numerical modeling methods with international competitiveness. The research directions meet those of the key industry development in Taiwan and match important state-of-the-art topics pursued in international photonics academic communities. This research team has recently achieved several related device technologies that not only were in the lead in Taiwan but also attracted international recognition. These technologies have great potentials of being further innovated and found practical applications. These achievements are briefed in the following. First, we have explored organic solar cells with inverted structures. The organic layer was sandwiched by two oxides to provide good protection on the organic materials for improved stability using full solution process. The cost could be very low and the production speed is potentially high for its compatibility with printing technology. Second, we established the only laboratory to successfully develop the analytical solution to explain the current-voltage characteristics of the organic light-emitting diode (OLED) with the presence of trap distribution in the organic materials. Third, the micro-structural and micro-spectral characteristics of a vertical-aligned liquid crystal display (VA-LCD) panel were obtained non-invasively for the first time. With 1-μm-axial and 2-μm-transversal resolutions, the cell gap profile beneath the patterned thin-film transistor of the VA-LCD panel can clearly be resolved. Furthermore, the photonic device modeling and design based on the techniques of computational electromagnetics are one of the strengths in this team. The research in this sub-project covers the following five topics: solar energy devices, light source devices, display devices, sensing devices, and numerical modeling for new interface structures and device applications.

Subproject 2 Integrated Platform for Intelligent Sensing Chips

    Recent research in the field of brain computer interface has demonstrated that monkeys and humans can move computer cursors and robotic arms directly by thought. These proof-of-concept laboratory demonstrations motivate the continuous development on VLSI chips for cortically-controlled neuroprosthetic devices. The implantable electrode arrays, multichannel recording ICs, and integrated wireless data telemetry circuits drive the research field toward the direction of long-duration and wireless experiments on freely moving subjects. In order to further improve the neuroprosthetics and achieve a clinical viable device, the bulk associated with the external computing systems has to be removed. The real-time signal processing tools for brain signals should be realized on chips.
 
    There are several design requirements imposed by the applications for the on-chip brain signal processing. Because of the limited space and power resource at the recording site, low power consumption and minimized area are two primary requirements for the portable or implantable neural prosthetic devices. Afterwards the high-density recording with a large number of channels is also required. The high-density recording can advance fundamental neuroscience studies and has the potential to improve the performance of neural prosthetic devices. The hardware should have enough processing capability to handle the raw cortical signals of multiple channels in a real time. The real-time processing capability removes the necessity of storing the large amount of raw data, which saves the power and area of the large memory. The prompt response can thus be achieved for the real-time applications. In addition, the wireless telemetry is important because the wires generally impose significant restrictions for subjects in the scientific experiments and the clinical applications. Transmitting signals wirelessly usually requires significant power especially for a large among of recording channels. On-chip information extraction before the wireless telemetry removes the redundant signals, which greatly compresses the data and the corresponding power of wireless telemetry.

    Successful proof-of-concept laboratory experiments motivate continued development for brain computer interface. Advances in implantable electrode arrays and miniaturized multichannel recording ICs enable long-duration, wireless and closed-loop experiments on freely moving subjects. To further improve clinically viable devices, the bulk associated with external systems must be eliminated. Thus a miniaturized processing-and-controlling system interfacing recording ICs and actuators in a real time is required. Low power consumption and minimized area are two primary requirements for implantable devices. Significant computational capabilities are needed to handle multichannel neural data in real time. Programmability is essential because of the variability of testing subjects and application requirements. A systematic hardware-software hierarchy is required to facilitate the integration and controlling flexibility over the functional blocks. It will be the way to succeed by connecting the advanced techniques on algorithm, architecture, and system levels to the application requirements.
For intelligent wireless mobile integrated circuits and systems, our group will be focused on reconfigurable/programmable implementation, an 84GHz CMOS transceiver, and a novel output current feedback technique for LED lighting applications. A flexible and reconfigurable/programmable implementation on an FPGA or GPU platform can bring exciting applications to current and future devices; an 84GHz CMOS transceiver will be realized and will have a great contribution to the academic and industry fields; a novel output current feedback technique for LED lighting applications is of great importance especially in industry since the cost of the driving solution would be quite reduced.
For intelligent medical electronic circuits and systems, our research proposal targets at developing portable physiological signal (EEG and ECG) detection system and signal processing techniques (by using HHT transformation) to analyze the cross-talk between human brain and heart. Successful research outcomes will unveil the link between these two vital human organs and promote healthy living of human beings.

    For intelligent embedded systems for cyber-physical systems, we will aim on developing the essential enabling technologies for user centric cyber-physical services and systems. These technologies enable low-energy, fully integrated, wireless connected cyber-physical systems.
For electronic design automation for intelligent integrated circuits and systems, we will provide design algorithms, methodology, and tools for all the addressed architecture and circuit designs to optimize the design cost, silicon area, power consumption, and design time, and to improve circuit performance at the same time.  Involved major tasks include, from front-end to back-end design processes, electronic system-level (ESL) design to boost the design productivity, formal verification to validate design correctness, logic synthesis to optimize Boolean functions, simulation to verify circuit timing behavior, physical design to optimize layout area and timing, testing to validate circuit function and timing, etc.

Subproject 3Millimeter-wave and System-in-Package Technologies

    The explosive development in wireless applications has necessitated the demands in electromagnetic bandwidth. Being scarce in the land and natural resource, Taiwan’s prosperity relies on fully nurturing of the human resource and better utilizing spectrum resource. It is thus important to strategically encourage millimeter-wave (mmW) researches for continuing development of ICT industry. Hence, the subproject is missionary in technology advancement and exploration of new applications in microwave and mmW spectrum for benefits of the human being.

    In order to fulfill the requirements of mass storage, personalization, and mobility in today’s highly integrated digital products, the IEEE 802 standard organization has formed a 60GHz Wireless Gigabit group to promote 802.11ad. Using the unlicensed band in MMW spectrum, e.g., 57-64 GHz by FCC 47 CFR 15.255, the multi-Gbps high-speed wireless communications with 7 GHz bandwidth has emerged innovative applications and great opportunities in various areas, such as HDTV/3DTV, medical equipments, and Kiosk systems. NTU microwave group has been globally leading in the mmW integrated circuits (MMIC) and system integration, and also actively involved in the IEEE 802 standardization process. To keep Taiwan’s momentum, the master piece of the group research is to develop the key components in the mmW multi-channel transceiver module, including the mmW system-on-chip (SoC), system in package (SiP), and miniature multi-antennas for higher integration, lower power consumption, and exploratory applications with WPAN/WLAN/ WiMax compatibility.

Subproject 4 Seamless Connectivity

    Although the contribution of telecoms to global CO2 emissions is small at first glance, the reality is that wireless telecoms will play an increasingly important role in total ICT related energy consumption, under the current fast growth of wireless data traffic and emerging new network architecture such as LTE and LTE-A. The research in the basic technologies for achieving green communication shall be able to reduce the power consumption in many wireless access networks, while maintaining the quality of service of various network. Our approach is to detect and predict the users’ behavior and the usage of applications, and then dynamically adjust their network connection mode, reduce radio resource allocation, and even re-configure the network and turn off certain communication components. We will propose an energy optimization model, with QoS as constraints, based on the fact that multiple access networks (3G/3.75G/4G etc) may coexist in the future cellular network. Since most user activities during the period of 12:00 AM – 7:00 AM is relatively small, even by the simple reconfiguration approach, one should be able to reduce the energy consumption up to 25%. Further improvement of the energy saving will rely on the proposed energy optimization model and redesign of the communication components. The considered components include base stations, DSL or FTTx nodes, and the CPE network nodes, such as WiFi AP, femtocell AP, and our research results should also help Taiwan’s communication industry to further improve their competiveness.

    Future communications will be characterized by an even higher QoS demand from the user under an even stringent requirement for efficient resource utilization. Cooperative and collaborative networking (CCN) thus plays a key role in providing rich application support (e.g. broadband access and seamless connectivity) out of scarce resource availability (e.g. energy and spectrum). Since future communication platforms will be highly heterogeneous encompassing primary and secondary radio access, smart power grid, and fiber-optic communication, CCN will be highly cross-disciplinary to employ theories from quantum computing, social networking, and molecular communications for solving the problems. In addition, to maximize user performance subject to limited resource constraints, CCN is highly optimized across different layers of the protocol stack spanning the physical, MAC, and routing layers. With the proposed CCN technologies, existing communication networks such as wireless mesh networks, vehicular ad hoc networks, and mobile communication systems will be effectively upgraded for 4G and machine-to-machine (M2M) communications. Therefore, CCN will be highly competitive both in academia and industry, in science and technology.

    In this five-year project, we will study and develop key technologies that enable DSA-based communications. In particular, we will apply game theoretic framework to DSA communications. The game theoretic framework will enable cooperative operation among self-organized DSA devices. We will also develop new protocols that use sequenced-based channel hopping to ensure communicating secondary devices to discover each other in a fully distributed manner. Practical issues such as pricing for DSA wireless service will also be considered. Our solution will alleviate the exhaustion of precious spectrum resources and facilitate the wide deployment of DSA communications.

    Based on the MIMO channel understanding, efficient and practical algorithms for synchronization and channel estimation can be designed, which can be applied to the 4G wireless communication systems.

    Through the cooperation with sub-project III, the multi-channel RF transceiver can be integrated with the baseband processor.  This cooperation model will increase the participants to have the system design capability.

Subproject 5 Media and Social Cloud Computing with Chinese Flavor

    Cloud and mobile computing are expected to be the key areas driving ICT innovations for the next decade, and we expect to have significant contributions on several fronts.

    First, our scientific research will achieve technology breakthroughs in the areas of cloud computing algorithms, cross-language translation, multimedia search, and mobile user interfaces. Focusing on Chinese culture related cloud informatics, our world-leading innovations will be shared with the academic community through publications at the top-tier international conferences and journals, further advancing NTU’s academic competitiveness and awareness internationally.

    Second, we plan to demonstrate our technical development by making the following two cloud services publicly available for users unfamiliar with Chinese: (1) Chinese language learning system, and (2) Multimedia food ordering services for Chinese restaurants.

    Third, world-leading Taiwanese companies are in the process of transforming from manufacturing to services, and our innovation will help advance the state of the art of these industries. Our research and demonstrating services are also aligned with Taiwanese Government’s “Six Key Emerging Industries” (Tourism & Travel and Cultural Creativity), and “Four Key Intelligent Industries” (Cloud Computing).


    Last, our project will help train the next generation of mobile and cloud computing talent through academic research, development, and technology transfer, and will help drive innovations in these areas for the next few decades.

Subproject 6 : Intelligent Diagnostic and Therapeutic Care System

    The aim of intelligent medical therapeutics (IMT) is to leverage the advanced technologies to improve the efficiency of the current therapeutic procedure. Diagnosis is a science for making judgment of the disease process by integrating the past medical history, symptoms, physical exam, lab and clinical imaging data in an attempt to ensure correct diagnosis and in turn to maximize therapeutic efficiency. With the advent of aging of our society, there is growing emphasis on the need for intelligent therapeutic care and biomedical instrument. The bioengineering is an interdisciplinary field that integrates engineering technology, biology and medicine in order to develop instruments and equipments, and to provide needed help for prevention, diagnosis, and treatment of human disease. It provides an opportunity for personalized medicine, and such development enables the general public to be more conveniently and comprehensively realize their own health conditions, and also to improve the ability as well as mechanism for self-health management. As a result, the intelligent diagnostic and therapeutic care system holds the promise of improving disease diagnosis, monitoring, and therapeutic methods, reducing the cost of health-care organization, and enhancing quality of care for general public. There are totally five topics which will be addressed under this sub-project:

Personalized Healthcare Service Decision Support System:
    To apply data mining technologies and analyze liver-cancer data extracted from their Electronic Health Record (EHR), and expect to achieve three sub-goals: (1) to develop a cross-national data mining platform to share research resources/experiences, (2) to provide early detection of diseases, and (3) to establish standardized treatment, pathway and guidelines.

Clinical Medical Image Diagnosis:
    In this project, the CAD systems will be developed with several imaging modalities including 2D/3D US, elastogrpahy, ABUS and MRI. Because there are several similar techniques used in these CAD systems, the CAD systems could be modularized. Also, the US recording, tracking system and portable PC-based US system are developed in the project.

Intelligent Diagnostic and Therapeutic Devices:
    This topic is to develop new robots more in line with the rehabilitation specifications and requirements, and then achieving the goal of realization of a world-class advanced rehabilitation robot. Besides, we will build up our smart CPSD algorithm and its hardware implementation toward streamline of clinical application. From medical aspects, such a novel approach possibly contributes to new disease model and thus leads to new therapeutic means, especially for home care users.

Healthcare System for Elderly People:
    The proposed system, which integrates technologies to monitor social signals in a retirement home setting will be helpful to dementia patients and their caregivers which aims to enhance the social activities participation of the elderly, thereby delay the degradation of cognitive ability and reduce the probability of dementia, in order to achieve better life quality and reduce the medical and healthcare cost. Our goal is to enable early detection of abnormal behavior amid daily social activities.

Data Mining on Clinical Databases:
    In recent years, the release of next-generation sequencing (NGS) platforms overcomes the limitation of microarrays by massively sequencing every piece of information of our genome. Recently, the 1000 genome pilot project generated 15 million of SNPs across multiple human populations. To date, there are more than 30 millions of SNPs in the NCBI dbSNP database, which is expected to increase as more low-MAF SNPs will be found.